Calcium Signalling and Disease: Molecular pathology of by Ernesto Carafoli, Marisa Brini

By Ernesto Carafoli, Marisa Brini

Authors spotlight numerous promising discoveries within the box of calcium signaling that offer new information regarding either genetic and purchased pathologies. Their discussions provide you with new insights into the underlying motives of congenital and bought ailments and aspect tips on how to new, much more promising learn and therapies.

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J. Flower, 2000, Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism. Br J Pharmacol. 130(2):289–98. , and W. L. van Heerde, 2006, Annexin A5 polymorphism (-1C>T) and the presence of anti-annexin A5 antibodies in the antiphospholipid syndrome. Ann Rheum Dis. , and A. Dejean, 1990, The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus.

And C. Thromb Res. 115 Suppl 1:77–81. , 2000, The annexinopathies: a new category of diseases. 1498(2,3):169–73. X. Wu, 2004, Antibody-mediated interference with annexins in the antiphospholipid syndrome. Thromb Res. 114(5, g6):383–9. L. Ortel, 2004, Detection of antibody-mediated reduction of annexin A5 anticoagulant activity in plasmas of patients with the antiphospholipid syndrome. 104(9):2783–90. F. M. L. Pryzdial, 1999, Annexin II enhances cytomegalovirus binding and fusion to phospholipid membranes.

And A. Dejean, 1990, The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus. Nature. 347(6293):558–61. , Schleicher, M. A. Noegel, 1995, The in vivo role of annexin VII (synexin): characterization of an annexin VII-deficient Dictyostelium mutant indicates an involvement in Ca(2+)-regulated processes. J. Cell Sci. 108 (Pt 5), 2065–2076. B. Babiychuk, 2005, Domain architecture of the smooth-muscle plasma membrane: regulation by annexins.

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