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Additional info for Biochemistry and Genetics Pretest Self-Assessment and Review 5/E
B. c. d. e. qxd 16 11/14/01 10:36 AM Page 16 Biochemistry and Genetics 19. Which of the following statements correctly describes eukaryotic nuclear chromosomal DNA? a. Each discontinuous piece making up the chromosomes of eukaryotes is about the same size as each prokaryotic chromosome b. Unlike bacterial DNA, no histones are associated with it c. It is not replicated semiconservatively d. It is a linear and unbranched molecule e. It is not associated with a specific membranous organelle 20. Xeroderma pigmentosum (278700) is an inherited human skin disease that causes a variety of phenotypic changes in skin cells exposed to sunlight.
A. b. c. d. e. Nicking, excision, replacement, sealing, recognition Sealing, recognition, nicking, excision, replacement Recognition, nicking, excision, replacement, sealing Nicking, sealing, recognition, excision, replacement Nicking, recognition, excision, sealing, replacement 30. Which of the following enzymes can be described as a DNA-dependent RNA polymerase? a. b. c. d. e. qxd 11/14/01 10:36 AM Page 19 DNA Structure, Replication, and Repair 19 31. Radiation therapy is employed for many cancers, including irradiation of the central nervous system to destroy lymphoblasts in leukemia.
The most likely mechanism for this mutation is a. b. c. d. e. Crossing over Two-base insertion Three-base deletion Nondisjunction Single-base substitution (point mutation) 16. Parents bring their newborn daughter to you for consultation about diagnosis and management. Their first two children, a boy and a girl, have a complete form of albinism (203100) with pink irides, blond hair, and pale skin. Which of the following represents your correct advice concerning the newborn child? a. b. c. d. e. A 1/8 risk for albinism and skin cancer from DNA deletions A 1/8 risk for albinism and skin cancer from DNA cross-linkage A 1/4 risk for albinism and skin cancer from DNA point mutations A 1/4 risk for albinism and skin cancer from DNA deletions A 1/4 risk for albinism and skin cancer from DNA cross-linkage 17.